Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity connected with bortezomib, a proteasome inhibitor Utilized in the remedy of a number of myeloma. Its synthesis or research is crucial for making sure the purity and security in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the therapy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound during the synthesis of imatinib, a drug that targets precise varieties of most cancers, like Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers which include breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their analyze is significant for optimizing the manufacturing system and making certain superior purity.
Lapatinib Intermediate vildagliptin intermediates (CAS NO. 231278-84-5): Lapatinib is employed to take care of breast cancer, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the treatment of breast cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and small cell lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This 5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde compound is linked to the synthesis of adamantane derivatives, that have numerous programs, which includes antiviral Houses.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-4 to regulate blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of various gluconic acid derivatives, which are used in foods, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication used to manage style 2 diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).